Association of Clinical Research Professionals (ACRP) Certified Professional Practice Exam

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True or False: Multi-center trials can occur at any phase of clinical development.

  1. True

  2. False

  3. Only in Phase 3 trials

  4. Only in Phase 2 and Phase 3

The correct answer is: True

Multi-center trials can indeed occur at any phase of clinical development, making the statement true. Such trials involve multiple study sites, which can enhance the generalizability of the findings, allow for the recruitment of a more diverse patient population, and improve the statistical power of the study by increasing the number of participants. These trials are not limited to just Phase 2 or Phase 3; they can also be conducted during Phase 1, particularly when the goal is to evaluate safety and dosing in a broader context or across different demographic groups. This flexibility is essential for various types of research aims and can greatly contribute to the efficiency and effectiveness of clinical development as a whole. Conducting multi-center trials at all phases can help address different research questions and support the drug development process comprehensively, reinforcing the importance of this design in clinical research.

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