What is the function of a Legally Acceptable Representative (LAR) in research?

The function of a Legally Acceptable Representative (LAR) in research is to consent on behalf of participants who are unable to provide informed consent themselves. This typically applies to individuals who may not have the capacity to understand the information necessary to make an informed decision about their participation in a research study, such as minors or individuals with cognitive impairments. The LAR is legally authorized to make decisions regarding participation in research, ensuring that the rights and welfare of the potential participant are protected.

In research ethics, obtaining informed consent is a crucial step, ensuring that participants understand the nature of the study, its risks, and benefits. However, situations arise where individuals cannot provide that consent, making the role of the LAR vital in upholding the ethical standards of research. This representative must be someone who is familiar with the participant's situation and interests, typically a family member or legal guardian, ensuring that the consent process remains aligned with the participant's values and preferences.